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Each month we feature a key journal, lifting restrictions on content to make it freely available to all, and providing additional insights into the team behind the journal, its history, and its content. This month...
Journal of Histotechnology
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An international journal demonstrating the cellular morphology, chemical composition and function of normal and abnormal tissue
• Complete back archive available online • Online submission, tracking and peer-review system • Fast-track online publication Visit the journal homepage for Instructions for Authors, to subscribe online, to download a library recommendation form, and more...
Editor's Choice Ten articles of interest cherry-picked by Editor-in-Chief Karen Burg, and free to download. It is my great pleasure to welcome you to a new era in the Journal of Histotechnology history. Examples of histotechnology enthusiasts include a basic scientist, working to uncover the mysteries of cellular mechanisms by unraveling the intra- and extracellular “codes”; a biomedical engineer, designing a hip stem that must have the appropriate surface texture for bone tissue integration; or a pathologist, observing uniquely different cellular behaviors in a tissue biopsy and seeking to provide personalized information for a particular patient. Over 34 years ago, the Journal was first launched to capture these very important ideas and methodologies of histotechnology. Thanks to a new partnership between Maney Publishing and the National Society for Histotechnology, you are now able to access this past wealth of information in digital form, as well as the future wealth yet to be developed. Technology is a means to translate science to reality; hence, I am particularly excited about our new digital archives, as technology is not useful unless it is easily identified and accessed. Indeed histotechnology is a means to translate medical science to reality and real world application. Without histotechnology and ready access to the related techniques and processes, clinical translation is severely curbed. The ten Editor’s Choice Articles of Interest are free for download and represent the diversity of important publications found in the Journal archives. I hope you enjoy these manuscripts; they represent a tiny fraction of exciting content found in 34 years of digital archives of the Journal of Histotechnology. Happy reading! Karen Burg • Demonstration of kappa and lambda light chains by dual chromogenic in situ hybridization of formalin-fixed, acid-decalcified, and paraffin-embedded bone marrow trephine biopsies, G Lang • Chromogens in multiple immunohistochemical staining used for visual assessment and spectral imaging: the colorful future, C van der Loos • Histology Career Day: a model for high school outreach, L C Benson and C A Parzel • Bone implants: processing, embedding, cutting, and histopathology, N Troiano and M Kacena • Histological processing of pH-sensitive hydrogels used in corneal implant applications, N Farooqui, D Myung, W Koh, et al. • Multimedia tools - creating a connection between histology and education, A Seegmiller, M Nelsen, A Wendel, et al. • Progress in the development of microscopical techniques for diagnostic pathology, M Titford • Optimization of central nervous system stereotactic needle and pituitary biopsies with HistoGel™ tissue-processing medium, M W Becher, J Hofecker, T L Moss and T W Abel • Decalcification of bone: literature review and practical study of various decalcifying agents, methods, and their effects on bone histology, G Callis and D Sterchi |
An interview with We interview Journal of Histotechnology Editor, Karen Burg, on what histotechnology is about, how the Journal was established, and the Journal's Writing Partnership Programme. Double-click the video to view at full-size.
A new frontier for immunohistochemistry quantification: machine-learning!
Immunohistochemical (IHC) techniques are generally applied for qualitative purposes. Typically the investigator makes a visual assessment of the amount of staining or categorizes the staining intensity in negative, 1+, 2+, or 3+. Needless to say, these assessments are variable among different observers. Machine-based systems performing these quantifications are not widely spread, and there is certainly no generally accepted standard as yet. It seems that both industry and investigators are still ‘waiting’ for a user-friendly system that is widely applicable for many different tasks. The recently introduced inForm™ software (Caliper Life Sciences, Hopkinton, MA) is an example of a system that benefits from a machine-learning approach. Read more and watch a PowerPoint demonstration of this software.
Bright Field In-situ Hybridization
The development of immunohistochemistry for diagnostic purposes during the 1980s is considered one of the most important advances in anatomic pathology. By the use of specific antibodies, different protein products can be visualized in tissue sections. Since then there have been important developments in molecular pathology and genetics, and the detection and visualization of DNA and RNA on tissue sections have been made possible recently by bright field in-situ hybridization. Read Stephen's report on the latest advances in bright field in-situ hybridization.
Microscopy
When the topic of microscopy comes up, there is not one particular technology from the multitude of ever changing/refining methodologies to focus on. The microscopy realm is a constant offering of new applications and capabilities. Read Diane's short review of the latest microscope technologies in the histotechnology field.
Histochemistry By Michael Titford
Read Michael's concise overview of histochemical methodologies and the role these methods have to play around the world and in the future.
A tour of the histology laboratory Have you ever wondered what happens to your biopsy specimen after you leave the doctor's office? Follow a specimen through the histology process at Fletcher Allen Health Care, from transporting the specimen to the lab, through grossing and fixation, processing, embedding, sectioning, staining, quality control, and finally, pathologist review. Double-click the video to view at full-size. Sign up for Table of Contents alerts Publication of the March 2011 issue is imminent - watch this space! Ensure you don't miss out on the latest issue of the journal. Sign up to receive an email alert when each new issue is published. |
View FREE CONTENT online! From 1 March to 15 April 2011 we are lifting all access restrictions on three years of Journal of Histotechnology content to make it available to you completely free of charge. To begin your free online trial simply fill out this quick form*, click 'submit' and follow the link to view all content marked with an *By submitting your details, you are opting in to join our histotechnology mailing list. Journal of the Month special offer!
Throughout March only we are offering discounts of up to Grab it while you can!
Histotechnology Professionals Day
The National Society for Histotechnology (NSH) sponsors an annual celebration of Histotechnology Professionals through Histotechnology Professionals Day (HPD) in March each year. Most would agree that the field is not well known among lay people. The society has been working to educate young people about histotechnology as a career option with the annual Career Day program and HPD is another opportunity to increase public awareness and also bring awareness to practitioners of other disciplines in healthcare. Test your Knowledge View the slides and answer the questions below correctly to be in with a chance of winning a $50 Amazon voucher!
Click on the images to view at full size. 1. What is the tissue shown in A? Email your answers* to marketing@maney.co.uk, along with your full name. Use the subject line 'Test your Knowledge'. *By submitting your answers, you are opting in to join our histotechnology mailing list.
New developments for the Journal of Histotechnology From March 2011, the Journal of Histotechnology is being published by Maney Publishing. What does this mean for the journal? • Online availability - from 2011 all current and archived journal content will be available for subscribers and members to view online via IngentaConnect. • Fast track publication - enables peer-reviewed, copyedited, author-approved articles to be published online in advance of the printed and online issue. As soon as an article is online via fast track it is searchable and can be cited. • CrossRef – this collaborative reference linking service enables readers to follow links from an article’s references to the online content of the cited article, if that article is available in electronic format. • Alerting – table of contents alerts and RSS feeds are available free of charge to inform readers of new content as soon as an issue is published online. • Online submission system - submit papers for consideration at www.editorialmanager.com/his |
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Meet the Editors Editor-in-Chief
A graduate of North Carolina State University (BS, Chemical Engineering) and Clemson University (MS, PhD, Bioengineering), Karen completed a tissue engineering postdoctoral fellowship at Carolinas Medical Center in Charlotte, North Carolina, before joining the faculty at Clemson University in 1999. In 2007, she was appointed Interim Vice Provost at Clemson University. Karen has given over 200 invited presentations on the subject of engineered tissues, including multiple invited presentations at Gordon Research Conferences and National Academies meetings. She is the inventor of record on four patents and nine patent applications; technologies from her laboratories served as the basis for one spin-off company. |
ffd Managing Editor
Victoria Artigliere has had an interesting and varied 13-year career in the areas of communications, media and public relations, and marketing. Victoria graduated phi beta kappa in 1991 with dual degrees in Journalism and Sociology from Indiana University. After college, Victoria worked on the editorial staff for two trade publications: In Touch Magazine for dental hygienists and Special Reports for family physicians, both published by Whittle Communications. When she moved to Charleston, SC, in 1992, Victoria worked for the Charleston Area Convention & Visitors Bureau and rose to be the Assistant Director of the Media & Public Relations Department. |
Founding Editor
The origin and history of the Journal of Histotechnology The Journal of Histotechnology was conceived in 1974 during the first membership meeting. I suggested to the Board of Directors (BOD) that there was a need to create a journal for our society. At first I was met with skepticism that the fledging society could support and fund such a project. However, with the remarkable insights of the Society’s founding president, Lee G Luna, Chairman of the Board, Dominic Europa, and Treasurer, John Koski, and with assistance by our executive director, Roberta Mosedale, and managing editor, Janet Pillar, the JOH was created. It was a day of triumph for everyone – it was decided to publish the journal!
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National Society for Histotechnology The National Society for Histotechnology is a non-profit organization, committed to the advancement of histotechnology, its practitioners and quality standards of practice through leadership, education and advocacy. The NSH is 4,500 members strong representing histology professionals from around the globe. It hosts a highly successful, annual Symposium/Convention, publishes a quarterly, world class journal, publishes the NSH INAction member newsletter, offers numerous merit awards and educational scholarships, develops and publishes educational resource materials, and prepares relevant standards and procedures for the profession. None of this could be achieved or sustained without the efforts of the many committed individuals who volunteer their time and energies to ensure its continued success. |
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Writing Partnership Program The Journal of Histotechnology Writing Partnership Program (WPP) was established to assist individuals in the process of writing a manuscript for the Journal. Often, individuals writing their first manuscript on histotechnology relating new methods, modifications, or technical hints need guidance through the publishing process. Writing Partners will help these individuals with manuscript composition using the JOH Instructions for Authors guidelines. Writing Partners are skilled in scientific writing and have previously published in JOH. They value diplomacy, confidentiality, privacy, patience, and constructive criticism, while providing examples and encouraging the author to write in his or her unique style. The WPP editorial processes may all be accomplished via e-mail communication. If you wish to work with a Writing Partner to complete your manuscript please contact Gayle Callis, Assistant Editor of the Journal of Histotechnology. Email: gayle.callis@bresnan.net |
Journal of Histotechnology is a MORE OpenChoice journal publishing open access papers as well as traditional subscription access or pay-per-view papers. Submit your paper online now Journal of Histoetchnology has its own online submission, tracking and peer-review system at Editorial Manager. Fast-track publication Journal of Histotechnology now offers fast-track publication, whereby accepted papers are made available online immediately following final corrections, enabling papers to be published ahead of formal distribution of the print issue. View Instructions for Authors. Next month... Chinese Studies |
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